ChemicalBook > CAS DataBase List > (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID

(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID

Product Name
(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
CAS No.
127910-31-0
Chemical Name
(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
Synonyms
CGP 37849;CGP 37849;CGP-37849;CGP37849;dl-2-amino-4-methyl-5-phosphono-3-*pentenoic acid;(E)-2-Amino-4-methyl-5-phosphonopent-3-enoic acid;(3E)-2-Amino-4-methyl-5-phosphono-3-pentanoic acid;(E)-(±)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID;3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, (3E)-;(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
CBNumber
CB0334453
Molecular Formula
C6H12NO5P
Formula Weight
209.14
MOL File
127910-31-0.mol
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(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Property

Boiling point:
523.1±60.0 °C(Predicted)
Density 
1.506±0.06 g/cm3(Predicted)
storage temp. 
Desiccate at +4°C
solubility 
H2O: ≥2mg/mL (warmed)
form 
powder
pka
1.83±0.10(Predicted)
color 
white to beige
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0050
Product name
CGP 37849
Purity
≥98% (HPLC)
Packaging
5mg
Price
$100
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0050
Product name
CGP 37849
Purity
≥98% (HPLC)
Packaging
25mg
Price
$500
Updated
2024/03/01
Tocris
Product number
1469
Product name
CGP 37849
Purity
≥99%(HPLC)
Packaging
50
Price
$649
Updated
2021/12/16
Tocris
Product number
1469
Product name
CGP 37849
Purity
≥99%(HPLC)
Packaging
10
Price
$156
Updated
2021/12/16
TRC
Product number
C583545
Product name
CGP 37849
Packaging
25mg
Price
$305
Updated
2021/12/16
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(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Chemical Properties,Usage,Production

Uses

CGP 37849 is a potent antagonist at NMDA receptors which results in anticonvulsant activity (1). In addition, it may antagonize NMDA-antagonistic induced antianxiety effects (2).

Biological Activity

Potent, selective and competitive NMDA receptor antagonist (K i = 35 nM). Anticonvulsive following oral administration in vivo .

storage

Desiccate at +4°C

(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID Suppliers

China 34 Europe 1 Germany 3 Switzerland 1 United Kingdom 2 United States 9 USA 1 Global 51
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127910-31-0, (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACIDRelated Search:

(2R,3E)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid 2-amino-4-methyl-5-phosphono-3-pentenoic acid (2R,3E)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid 1-ethyl ester (2S,3E)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid (2S,3E)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid 1-ethyl ester 2-AMINO-3-BUTENOIC ACID ALLYLPHOSPHONIC ACID CGP 39653, [PROPYL-2,3,3H]- (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID ETHYL ESTER,(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID ETHYLESTHER

  • dl-2-amino-4-methyl-5-phosphono-3-*pentenoic acid
  • (3E)-2-Amino-4-methyl-5-phosphono-3-pentanoic acid
  • (E)-2-Amino-4-methyl-5-phosphonopent-3-enoic acid
  • (E)-(±)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
  • CGP 37849
  • (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID
  • CGP 37849;CGP-37849;CGP37849
  • 3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, (3E)-
  • 127910-31-0
  • C6H12NO5P
  • Glutamate receptor
  • Glutamate